Bruna Diirr, Claudia Cappelli: An increasingly dynamic, unpredictable and challenging environment leads organizations to cross their own borders and establish partnerships to other organizations for remaining competitive. This cross-organizational relationship allows participating organizations to share resources with each other and collaborate to better handle an identified opportunity for joint work. However, besides having a mutual or compatible goal, it is common that these organizations face several challenges during the partnership. The present research aims to explore the cross-organizational relationship management. To this end, this paper outlines the systematic literature review performed to understand the collaboration and relationship establishment between different organizations and organize an ICT related body of knowledge about the topic. A discussion about the findings, challenges and open issues identified from the retrieved literature is also provided to guide further work.